Traditional medicinal benefits of leaves,bark, fruit and seed of A. muricata have beenthe emphasis of myriad medicinal routines. The most significantly usedpreparation in traditional medicine is the decoction of bark, root, seed orleaf and applications are wide-ranging. The ingestion of leaves decoction isused as analgesic and also it is used to cope with discomfort accompanyingcolds, flu and asthma; and to treat cutaneous (external) and internalparasites.

The use of leaves to treat malaria is very substantial. The fruit isnot only cherished as food, but the juice is used as galactogogue to treatdiarrhea, heart and liver diseases, and against intestinal parasites. Customary therapeutic qualities of A. muricata have been recognized intropical locales to ponder different afflictions, for example, fever, torment,respiratory and skin disease, bacterial infections, hypertension, aggravation,diabetes and cancer. There havebeen a number of reports on the ethno-medical uses of A.muricata leavesincluding treatments for hypertension, diabetes and cancer.

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Most parts of the A. muricata tree,similar to that of the  other Annona species,namely A. squamosa and A. reticulata are widelyused as local and habitual medicines contrary to a large number of humaninflamations, infections and disorders. The pulp of the fruit is used asnatural medicine for joint pains, dysentery, neuralgia, diarrhea, rheumatism,fever, malaria, parasites, skin rushes and worms, and  also is eaten to increase mother’s milk afterparturition.

The leaves are used to control cystitis, , body aches anddiabetes. Additionally, the administration of the leaf’s decoction is thoughtto display anti-rheumatic and neuralgic effects. In addition, the cooked leavesare topically used to treat abscesses and rheumatism that was reported by de Sousa OV and colleagues.(9) The crushed seeds arethought to have anthelmintic activities antaagonistic to external and internalworms. In tropical Africa, the plant is employed as an astringent pesticide,and insecticide; along this it is used to treat coughs, pain and skin diseases.In India, the fruit and flower are used as remedies against catarrh, while theroot-bark and leaves are well known to have an anti phlogistic and anthelminticactivities which was worked uponby Adewole SO, Ojewole J.(2)In Malaysia, the crude extract of A.

muricata and A. squamosa is used as a syrup on the headto buffer from fainting. In South America and tropical Africa, includingNigeria, leaves of A.muricata are implemented as anethnomedicine opposed to tumors and cancer. Moreover, the smooth musclerelaxant, hypotensive hypoglycemic, anti-inflammatory, sedative, andantispasmodic effects accredit to the leaves, barks and roots of A.muricata. Moreover along with the ethnomedicinal uses, the fruits arewidely employed for the preparation of beverages, ice creams,and syrups (3, 21, 23,26) .